萤光素酶细胞系

Luciferase cell lines (i.e. luciferase labeled cell lines) constitutively express firefly luciferase. Luciferase can catalyze the oxidation of luciferin. In the process of luciferin oxidation, it will emit biological fluorescence, and the luminous intensity can be accurately quantified. Therefore, Luciferase cell line can be used for new drug/treatment discovery, such as lead compound screening, efficacy evaluation, cell therapy discovery, etc. In addition, bioluminescence imaging with luciferase is a major method for studying in vivo imaging. Therefore, Luciferase tagged cells are usually applied to the construction of a CDX (cell-line-derived xenograft) model, which can directly image in vivo. This method can better simulate the growth environment of tumor cells, and is beneficial for the in vivo research of tumor cell proliferation and drug screening.

Product feature: Vitro Biotech provides low-passage Luciferase labeled cell lines. This category are tested for luciferase activity. For some of the Luciferase stable cell lines that are commonly used in CDX model, Vitro Biotech also performed mouse tumorigenicity tests.

If your preferred luciferase tagged cell line is not on the list, please contact us to get a quote for the stable cell line customization service. A luciferase labeled cell line can be obtained as soon as 6 weeks.